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An enhancer RNA recruits MLL1 to regulate transcription of Myb
The Myb proto-oncogene encodes the transcription factor c-MYB, which is critical for hematopoiesis. Distant enhancers of Myb form a hub of interactions with the Myb promoter. We identified a long non-coding RNA (Myrlin) originating from the −81 kb murine Myb enhancer. Myrlin and Myb are coordinately...
Autores principales: | Kim, Juhyun, Diaz, Luis F., Miller, Matthew J., Leadem, Benjamin, Krivega, Ivan, Dean, Ann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557664/ https://www.ncbi.nlm.nih.gov/pubmed/37808852 http://dx.doi.org/10.1101/2023.09.26.559528 |
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