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A Scalable Staining Strategy for Whole-Brain Connectomics

Mapping the complete synaptic connectivity of a mammalian brain would be transformative, revealing the pathways underlying perception, behavior, and memory. Serial section electron microscopy, via membrane staining using osmium tetroxide, is ideal for visualizing cells and synaptic connections but,...

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Detalles Bibliográficos
Autores principales: Lu, Xiaotang, Wu, Yuelong, Schalek, Richard L., Meirovitch, Yaron, Berger, Daniel R., Lichtman, Jeff W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557665/
https://www.ncbi.nlm.nih.gov/pubmed/37808722
http://dx.doi.org/10.1101/2023.09.26.558265