Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion

The ribosome is an essential drug target as many classes of clinically important antibiotics bind and inhibit its functional centers. The catalytic peptidyl transferase center (PTC) is targeted by the broadest array of inhibitors belonging to several chemical classes. One of the most abundant and cl...

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Detalles Bibliográficos
Autores principales: Aleksandrova, Elena V., Wu, Kelvin J. Y., Tresco, Ben I. C., Syroegin, Egor A., Killeavy, Erin E., Balasanyants, Samson M., Svetlov, Maxim S., Gregory, Steven T., Atkinson, Gemma C., Myers, Andrew G., Polikanov, Yury S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557674/
https://www.ncbi.nlm.nih.gov/pubmed/37808676
http://dx.doi.org/10.1101/2023.09.27.559749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557674/
https://www.ncbi.nlm.nih.gov/pubmed/37808676
http://dx.doi.org/10.1101/2023.09.27.559749

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