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PspA-mediated aggregation protects Streptococcus pneumoniae against desiccation on fomites

Streptococcus pneumoniae (Spn) resides in the nasopharynx where it can disseminate to cause disease. One key Spn virulence factor is pneumococcal surface protein A (PspA), which promotes survival by blocking the antimicrobial peptide lactoferricin. PspA has also been shown to mediate attachment to d...

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Detalles Bibliográficos
Autores principales: Lane, Jessica R., Tata, Muralidhar, Yasmin, Rahena, Im, Hansol, Briles, David E., Orihuela, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557681/
https://www.ncbi.nlm.nih.gov/pubmed/37808718
http://dx.doi.org/10.1101/2023.09.27.559802