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PspA-mediated aggregation protects Streptococcus pneumoniae against desiccation on fomites
Streptococcus pneumoniae (Spn) resides in the nasopharynx where it can disseminate to cause disease. One key Spn virulence factor is pneumococcal surface protein A (PspA), which promotes survival by blocking the antimicrobial peptide lactoferricin. PspA has also been shown to mediate attachment to d...
Autores principales: | Lane, Jessica R., Tata, Muralidhar, Yasmin, Rahena, Im, Hansol, Briles, David E., Orihuela, Carlos J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557681/ https://www.ncbi.nlm.nih.gov/pubmed/37808718 http://dx.doi.org/10.1101/2023.09.27.559802 |
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