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Nuclear corepressors NCOR1 and NCOR2 entrain thymocyte signaling, selection, and emigration

T cell development proceeds via discrete stages that require both gene induction and gene repression. Transcription factors direct gene repression by associating with corepressor complexes containing chromatin-remodeling enzymes; the corepressors NCOR1 and NCOR2 recruit histone deacetylases to these...

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Detalles Bibliográficos
Autores principales: David, Natalie A., Lee, Robin D., LaRue, Rebecca S., Joo, Sookyong, Farrar, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557688/
https://www.ncbi.nlm.nih.gov/pubmed/37808728
http://dx.doi.org/10.1101/2023.09.27.559810