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CRISPR-Cas inhibits plasmid transfer and immunizes bacteria against antibiotic resistance acquisition in manure

The horizontal transfer of antibiotic resistance genes among bacteria is a pressing global issue. The bacterial defense system CRISPR-Cas acts as a barrier to the spread of antibiotic resistance plasmids, and CRISPR-Cas-based antimicrobials can be effective to selectively deplete antibiotic-resistan...

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Detalles Bibliográficos
Autores principales: Upreti, Chahat, Kumar, Pranav, Durso, Lisa M., Palmer, Kelli L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557689/
https://www.ncbi.nlm.nih.gov/pubmed/37808752
http://dx.doi.org/10.1101/2023.09.26.559507