Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise

Endurance exercise is an important health modifier. We studied cell-type specific adaptations of human skeletal muscle to acute endurance exercise using single-nucleus (sn) multiome sequencing in human vastus lateralis samples collected before and 3.5 hours after 40 min exercise at 70% VO(2)max in f...

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Detalles Bibliográficos
Autores principales: Rubenstein, Aliza B., Smith, Gregory R., Zhang, Zidong, Chen, Xi, Chambers, Toby L., Ruf-Zamojski, Frederique, Mendelev, Natalia, Cheng, Wan Sze, Zamojski, Michel, Amper, Mary Anne S., Nair, Venugopalan D., Marderstein, Andrew R., Montgomery, Stephen B., Troyanskaya, Olga G., Zaslavsky, Elena, Trappe, Todd, Trappe, Scott, Sealfon, Stuart C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557702/
https://www.ncbi.nlm.nih.gov/pubmed/37808658
http://dx.doi.org/10.1101/2023.09.26.558914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557702/
https://www.ncbi.nlm.nih.gov/pubmed/37808658
http://dx.doi.org/10.1101/2023.09.26.558914

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