Acute pharmacodynamic responses to sitagliptin: Drug-induced increase in early insulin secretion in oral glucose tolerance test

AIM: DPP4 inhibitors are widely prescribed as treatments for type 2 diabetes. Because drug responses vary among individuals, we initiated investigations to identify genetic variants associated with the magnitude of drug responses. METHODS: Sitagliptin (100 mg) was administered to 47 healthy voluntee...

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Detalles Bibliográficos
Autores principales: Beitelshees, Amber L., Streeten, Elizabeth A., Yazdi, Zhinous Shahidzadeh, Whitlatch, Hilary B., Mitchell, Braxton D., Shuldiner, Alan R., Montasser, May E., Taylor, Simeon I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557823/
https://www.ncbi.nlm.nih.gov/pubmed/37808823
http://dx.doi.org/10.1101/2023.09.24.23296026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557823/
https://www.ncbi.nlm.nih.gov/pubmed/37808823
http://dx.doi.org/10.1101/2023.09.24.23296026

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