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Advancing precision oncology through systematic germline and tumor genetic analysis: The oncogenetic point of view on findings from a prospective multicenter clinical trial of 666 patients

INTRODUCTION: With the emergence of targeted therapies, there is a need to accurately identify more tumor biomarkers. The EXOMA trial was designed to offer tumor and germline exome sequencing (ES) to patients with solid malignant tumors and facing therapeutic failure. As hereditary cancer predisposi...

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Detalles Bibliográficos
Autores principales: Mazel, Benoit, Bertolone, Geoffrey, Baurand, Amandine, Cosset, Elodie, Sawka, Caroline, Robert, Marion, Gautier, Elodie, Lançon, Allan, Réda, Manon, Favier, Laure, Dérangère, Valentin, Richard, Corentin, Binquet, Christine, Boidot, Romain, Goussot, Vincent, Albuisson, Juliette, Ghiringhelli, François, Faivre, Laurence, Nambot, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557826/
https://www.ncbi.nlm.nih.gov/pubmed/37694493
http://dx.doi.org/10.1002/cam4.6498