Alternative promoters and splicing create multiple functionally distinct isoforms of oestrogen receptor alpha in breast cancer and healthy tissues

BACKGROUND: Oestrogen receptor alpha (ER) is involved in cell growth and proliferation and functions as a transcription factor, a transcriptional coregulator, and in cytoplasmic signalling. It affects, for example, bone, endometrium, ovaries and mammary epithelium. It is a key biomarker in clinical...

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Detalles Bibliográficos
Autores principales: Balcazar Lopez, Carlos Enrique, Albrecht, Juliane, Hafstað, Völundur, Börjesson Freitag, Cornelia, Vallon‐Christersson, Johan, Bellodi, Cristian, Persson, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557849/
https://www.ncbi.nlm.nih.gov/pubmed/37676103
http://dx.doi.org/10.1002/cam4.6508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557849/
https://www.ncbi.nlm.nih.gov/pubmed/37676103
http://dx.doi.org/10.1002/cam4.6508

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