Integration of metabolomics and machine learning revealed tryptophan metabolites are sensitive biomarkers of pemetrexed efficacy in non‐small cell lung cancer

BACKGROUND: Anti‐folate drug pemetrexed is a vital chemotherapy medication for non‐small cell lung cancer (NSCLC). Its response varies widely and often develops resistance to the treatment. Therefore, it is urgent to identify biomarkers and establish models for drug efficacy evaluation and predictio...

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Detalles Bibliográficos
Autores principales: Sun, Runbin, Fei, Fei, Wang, Min, Jiang, Junyi, Yang, Guangyu, Yang, Na, Jin, Dandan, Xu, Zhi, Cao, Bei, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557891/
https://www.ncbi.nlm.nih.gov/pubmed/37605514
http://dx.doi.org/10.1002/cam4.6446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557891/
https://www.ncbi.nlm.nih.gov/pubmed/37605514
http://dx.doi.org/10.1002/cam4.6446

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