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Influence of CYP450 Enzymes and ABCB1 Polymorphisms on Clopidogrel Response in Moroccan Patients with Acute Coronary Syndromes

INTRODUCTION: Clopidogrel is an antiplatelet prodrug primarily prescribed to prevent or treat acute coronary syndrome (ACS) or acute ischemic stroke (IS), polymorphisms of genes encoding cytochrome P-450 (CYP) and P-glycoprotein transporter, could affect the efficiency of clopidogrel absorption and...

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Detalles Bibliográficos
Autores principales: Mouhrach, Ismail, Bouguenouch, Laila, Kamal, Adil, Meriame, Abbassi, El Khorb, Nada, El Azami El Idrissi, Mohammed, Akoudad, Hafid, Bekkari, Hicham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557961/
https://www.ncbi.nlm.nih.gov/pubmed/37810546
http://dx.doi.org/10.2147/PGPM.S390092