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Advanced Glycation End Products Downregulate Connexin 43 and Connexin 40 in Diabetic Atrial Myocytes via the AMPK Pathway

PURPOSE: Diabetes mellitus is an independent risk factor for atrial fibrillation (AF), which may be related to accumulation of advanced glycation end products (AGEs). However, the mechanisms involved are not completely clear. Abnormality of gap junction proteins, especially connexin 43 (Cx43) and co...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Liu, Huan-Huan, Zhang, Lei, Zhang, Xiao-Lu, Zhang, Jie, Li, Feng, Zhao, Ning, Zhang, Zhi-Yuan, Kong, Qi, Liu, Xiao-Yu, Wu, Ying, Yu, Zhi-Ming, Qian, Ling-Ling, Wang, Ru-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557968/
https://www.ncbi.nlm.nih.gov/pubmed/37810573
http://dx.doi.org/10.2147/DMSO.S419189