Detecting Human Epidermal Growth Factor Receptor 2 (HER2) Amplification: Proof of Concept of an Alternative Approach

Background: There are multiple genes that are co-amplified along with human epidermal growth factor receptor 2 (HER2) in chromosome 17. GRB7 and PGAP3 are two such genes. We hypothesize that the protein products of these genes may serve as immunohistochemistry (IHC) markers for detecting HER2 amplif...

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Detalles Bibliográficos
Autores principales: Mudgal, Shikha, Paul, Pranoy, Ravi, Bina, Agrawal, Shruti, Kalra, Arnav, Rao, Shalinee, Chowdhury, Nilotpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558136/
https://www.ncbi.nlm.nih.gov/pubmed/37809181
http://dx.doi.org/10.7759/cureus.44785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558136/
https://www.ncbi.nlm.nih.gov/pubmed/37809181
http://dx.doi.org/10.7759/cureus.44785

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