Cargando…

SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury

Sirtuins (SIRT) exhibit deacetylation or ADP-ribosyltransferase activity and regulate a wide range of cellular processes in the nucleus, mitochondria, and cytoplasm. The role of the only sirtuin that resides in the cytoplasm, SIRT2, in the development of ischemic injury and cardiac hypertrophy is no...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xiaoyan, Chang, Hsiang-Chun, Tatekoshi, Yuki, Mahmoodzadeh, Amir, Balibegloo, Maryam, Najafi, Zeinab, Wu, Rongxue, Chen, Chunlei, Sato, Tatsuya, Shapiro, Jason, Ardehali, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558204/
https://www.ncbi.nlm.nih.gov/pubmed/37728319
http://dx.doi.org/10.7554/eLife.85571