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In silico and in vitro inhibition of host-based viral entry targets and cytokine storm in COVID-19 by ginsenoside compound K

SARS-CoV-2 is a novel coronavirus that emerged as an epidemic, causing a respiratory disease with multiple severe symptoms and deadly consequences. ACE-2 and TMPRSS2 play crucial and synergistic roles in the membrane fusion and viral entry of SARS-CoV-2 (COVID-19). The spike (S) protein of SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Boopathi, Vinothini, Nahar, Jinnatun, Murugesan, Mohanapriya, Subramaniyam, Sathiyamoorthy, Kong, Byoung Man, Choi, Sung-Keun, Lee, Chang-Soon, Ling, Li, Yang, Dong Uk, Yang, Deok Chun, Mathiyalagan, Ramya, Chan Kang, Se
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558348/
https://www.ncbi.nlm.nih.gov/pubmed/37809955
http://dx.doi.org/10.1016/j.heliyon.2023.e19341