Cargando…

The association between circulatory, local pancreatic PCSK9 and type 2 diabetes mellitus: The effects of antidiabetic drugs on PCSK9

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a potent modulator of cholesterol metabolism and plays a crucial role in the normal functioning of pancreatic islets and the progression of diabetes. Islet autocrine PCSK9 deficiency can lead to the enrichment of low-density lipoprotein (LDL)...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Fengyuan, Li, En, Yang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558357/
https://www.ncbi.nlm.nih.gov/pubmed/37809924
http://dx.doi.org/10.1016/j.heliyon.2023.e19371