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Linking MS1 and MS2 signals in positive and negative modes of LC-HRMS in untargeted metabolomics using the ROIMCR approach

Data-independent acquisition (DIA) mode in liquid chromatography (LC) high-resolution mass spectrometry (HRMS) has emerged as a powerful strategy in untargeted metabolomics for detecting a broad range of metabolites. However, the use of this approach also represents a challenge in the analysis of th...

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Detalles Bibliográficos
Autores principales: Yamamoto, Flávia Yoshie, Pérez-López, Carlos, Lopez-Antia, Ana, Lacorte, Silvia, de Souza Abessa, Denis Moledo, Tauler, Romà
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558381/
https://www.ncbi.nlm.nih.gov/pubmed/37587312
http://dx.doi.org/10.1007/s00216-023-04893-3