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Mechanical stress confers nuclear and functional changes in derived leukemia cells from persistent confined migration

Nuclear deformability plays a critical role in cell migration. During this process, the remodeling of internal components of the nucleus has a direct impact on DNA damage and cell behavior; however, how persistent migration promotes nuclear changes leading to phenotypical and functional consequences...

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Detalles Bibliográficos
Autores principales: de Lope-Planelles, Ana, González-Novo, Raquel, Madrazo, Elena, Peralta-Carrero, Gracia, Cruz Rodríguez, María Pilar, Zamora-Carreras, Héctor, Torrano, Verónica, López-Menéndez, Horacio, Roda-Navarro, Pedro, Monroy, Francisco, Redondo-Muñoz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558412/
https://www.ncbi.nlm.nih.gov/pubmed/37801090
http://dx.doi.org/10.1007/s00018-023-04968-5