Genomic analysis of advanced breast cancer tumors from talazoparib-treated gBRCA1/2mut carriers in the ABRAZO study

These analyses explore the impact of homologous recombination repair gene mutations, including BRCA1/2 mutations and homologous recombination deficiency (HRD), on the efficacy of the poly(ADP-ribose) polymerase (PARP) inhibitor talazoparib in the open-label, two-cohort, Phase 2 ABRAZO trial in germl...

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Detalles Bibliográficos
Autores principales: Turner, Nicholas C., Laird, A. Douglas, Telli, Melinda L., Rugo, Hope S., Mailliez, Audrey, Ettl, Johannes, Grischke, Eva-Maria, Mina, Lida A., Balmaña, Judith, Fasching, Peter A., Hurvitz, Sara A., Hopkins, Julia F., Albacker, Lee A., Chelliserry, Jijumon, Chen, Ying, Conte, Umberto, Wardley, Andrew M., Robson, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558443/
https://www.ncbi.nlm.nih.gov/pubmed/37803017
http://dx.doi.org/10.1038/s41523-023-00561-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558443/
https://www.ncbi.nlm.nih.gov/pubmed/37803017
http://dx.doi.org/10.1038/s41523-023-00561-y

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