Chronic treatment with D2-antagonist haloperidol leads to inhibitory/excitatory imbalance in striatal D1-neurons

Striatal dysfunction has been implicated in the pathophysiology of schizophrenia, a disorder characterized by positive symptoms such as hallucinations and delusions. Haloperidol is a typical antipsychotic medication used in the treatment of schizophrenia that is known to antagonize dopamine D2 recep...

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Detalles Bibliográficos
Autores principales: Santa, Cátia, Rodrigues, Diana, Coelho, Joana F., Anjo, Sandra I., Mendes, Vera M., Bessa-Neto, Diogo, Dunn, Michael J., Cotter, David, Baltazar, Graça, Monteiro, Patrícia, Manadas, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558446/
https://www.ncbi.nlm.nih.gov/pubmed/37803004
http://dx.doi.org/10.1038/s41398-023-02609-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558446/
https://www.ncbi.nlm.nih.gov/pubmed/37803004
http://dx.doi.org/10.1038/s41398-023-02609-w

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