Amino acid transporter SLC38A5 is a tumor promoter and a novel therapeutic target for pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) cells have a great demand for nutrients in the form of sugars, amino acids, and lipids. Particularly, amino acids are critical for cancer growth and, as intermediates, connect glucose, lipid and nucleotide metabolism. PDAC cells meet these requirements by upre...

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Detalles Bibliográficos
Autores principales: Sniegowski, Tyler, Rajasekaran, Devaraja, Sennoune, Souad R., Sunitha, Sukumaran, Chen, Fang, Fokar, Mohamed, Kshirsagar, Sudhir, Reddy, P. Hemachandra, Korac, Ksenija, Mahmud Syed, Mosharaf, Sharker, Tanima, Ganapathy, Vadivel, Bhutia, Yangzom D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558479/
https://www.ncbi.nlm.nih.gov/pubmed/37803043
http://dx.doi.org/10.1038/s41598-023-43983-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558479/
https://www.ncbi.nlm.nih.gov/pubmed/37803043
http://dx.doi.org/10.1038/s41598-023-43983-1

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