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Amino acid transporter SLC38A5 is a tumor promoter and a novel therapeutic target for pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) cells have a great demand for nutrients in the form of sugars, amino acids, and lipids. Particularly, amino acids are critical for cancer growth and, as intermediates, connect glucose, lipid and nucleotide metabolism. PDAC cells meet these requirements by upre...
Autores principales: | Sniegowski, Tyler, Rajasekaran, Devaraja, Sennoune, Souad R., Sunitha, Sukumaran, Chen, Fang, Fokar, Mohamed, Kshirsagar, Sudhir, Reddy, P. Hemachandra, Korac, Ksenija, Mahmud Syed, Mosharaf, Sharker, Tanima, Ganapathy, Vadivel, Bhutia, Yangzom D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558479/ https://www.ncbi.nlm.nih.gov/pubmed/37803043 http://dx.doi.org/10.1038/s41598-023-43983-1 |
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