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Mucosal application of the broadly neutralizing antibody 10-1074 protects macaques from cell-associated SHIV vaginal exposure

Passive immunization using broadly neutralizing antibodies (bNAbs) is investigated in clinical settings to inhibit HIV-1 acquisition due to the lack of a preventive vaccine. However, bNAbs efficacy against highly infectious cell-associated virus transmission has been overlooked. HIV-1 transmission m...

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Detalles Bibliográficos
Autores principales: Suphaphiphat, Karunasinee, Desjardins, Delphine, Lorin, Valérie, Dimant, Nastasia, Bouchemal, Kawthar, Bossevot, Laetitia, Galpin-Lebreau, Maxence, Dereuddre-Bosquet, Nathalie, Mouquet, Hugo, Le Grand, Roger, Cavarelli, Mariangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558491/
https://www.ncbi.nlm.nih.gov/pubmed/37803011
http://dx.doi.org/10.1038/s41467-023-41966-4