Targeting c-Jun inhibits fatty acid oxidation to overcome tamoxifen resistance in estrogen receptor-positive breast cancer

Tamoxifen-based endocrine therapy remains a major adjuvant therapy for estrogen receptor (ER)-positive breast cancer (BC). However, many patients develop tamoxifen resistance, which results in recurrence and poor prognosis. Herein, we show that fatty acid oxidation (FAO) was activated in tamoxifen-r...

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Detalles Bibliográficos
Autores principales: Jiang, Cen, Zhu, Youzhi, Chen, Huaying, Lin, Junyu, Xie, Ruiwang, Li, Weiwei, Xue, Jiajie, Chen, Ling, Chen, Xiangjin, Xu, Sunwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558541/
https://www.ncbi.nlm.nih.gov/pubmed/37803002
http://dx.doi.org/10.1038/s41419-023-06181-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558541/
https://www.ncbi.nlm.nih.gov/pubmed/37803002
http://dx.doi.org/10.1038/s41419-023-06181-5

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