CD3-immunotoxin mediated depletion of T cells in lymphoid tissues of rhesus macaques

Selective T-cell depletion prior to cell or organ transplantation is considered a preconditioning regimen to induce tolerance and immunosuppression. An immunotoxin consisting of a recombinant anti-CD3 antibody conjugated with diphtheria toxin was used to eliminate T-cells. It showed significant T-ce...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Suryawanshi, Gajendra W., Kim, Shihyoung, Guan, Xin, Bonifacino, Aylin C., Metzger, Mark E., Donahue, Robert E., Kim, Sanggu, Chen, Irvin S.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558572/
https://www.ncbi.nlm.nih.gov/pubmed/37810095
http://dx.doi.org/10.1016/j.heliyon.2023.e19435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558572/
https://www.ncbi.nlm.nih.gov/pubmed/37810095
http://dx.doi.org/10.1016/j.heliyon.2023.e19435

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