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CD3-immunotoxin mediated depletion of T cells in lymphoid tissues of rhesus macaques
Selective T-cell depletion prior to cell or organ transplantation is considered a preconditioning regimen to induce tolerance and immunosuppression. An immunotoxin consisting of a recombinant anti-CD3 antibody conjugated with diphtheria toxin was used to eliminate T-cells. It showed significant T-ce...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558572/ https://www.ncbi.nlm.nih.gov/pubmed/37810095 http://dx.doi.org/10.1016/j.heliyon.2023.e19435 |