Cargando…
Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies
Large-scale compound screens are a powerful model system for understanding variability of treatment response and discovering druggable tumor vulnerabilities of hematological malignancies. However, as mostly performed in a monoculture of tumor cells, these assays disregard modulatory effects of the i...
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society of Hematology
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558604/ https://www.ncbi.nlm.nih.gov/pubmed/37352275 http://dx.doi.org/10.1182/bloodadvances.2022009652 |