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Targeting conditioned media dependencies and FLT-3 in chronic lymphocytic leukemia

The importance of the stromal microenvironment in chronic lymphocytic leukemia (CLL) pathogenesis and drug resistance is well established. Despite recent advances in CLL therapy, identifying novel ways to disrupt interactions between CLL and its microenvironment may identify new combination partners...

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Detalles Bibliográficos
Autores principales: Parvin, Salma, Aryal, Aditi, Yin, Shanye, Fell, Geoffrey G., Davids, Matthew S., Wu, Catherine J., Letai, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558618/
https://www.ncbi.nlm.nih.gov/pubmed/37428863
http://dx.doi.org/10.1182/bloodadvances.2022008207