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Palmitoyltransferase ZDHHC3 Aggravates Nonalcoholic Steatohepatitis by Targeting S‐Palmitoylated IRHOM2 (Adv. Sci. 28/2023)

ZDHHC3 In article number 2302130, Minxuan Xu, Jun Tan, Benkui Zou, Bochu Wang, and co‐workers identify ZDHHC3 as a novel and critical acetyltransferase required for the IRHOM2 palmitoylation. Metabolic stresses‐triggered increase of ZDHHC3 maintains palmitoylated IRHOM2 accumulation by blocking its...

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Detalles Bibliográficos
Autores principales: Xu, Minxuan, Tan, Jun, Zhu, Liancai, Ge, Chenxu, Zhang, Yi, Gao, Fufeng, Dai, Xianling, Kuang, Qin, Chai, Jie, Zou, Benkui, Wang, Bochu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558637/
http://dx.doi.org/10.1002/advs.202370191