Pre‐rRNA Facilitates TopBP1‐Mediated DNA Double‐Strand Break Response

In response to genotoxic stress‐induced DNA damage, TopBP1 mediates ATR activation for signaling transduction and DNA damage repair. However, the detailed molecular mechanism remains elusive. Here, using unbiased protein affinity purification and RNA sequencing, it is found that TopBP1 is associated...

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Detalles Bibliográficos
Autores principales: Xin, Di, Gai, Xiaochen, Ma, Yidi, Li, Zexing, Li, Qilin, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558638/
https://www.ncbi.nlm.nih.gov/pubmed/37582658
http://dx.doi.org/10.1002/advs.202206931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558638/
https://www.ncbi.nlm.nih.gov/pubmed/37582658
http://dx.doi.org/10.1002/advs.202206931

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