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Pre‐rRNA Facilitates TopBP1‐Mediated DNA Double‐Strand Break Response
In response to genotoxic stress‐induced DNA damage, TopBP1 mediates ATR activation for signaling transduction and DNA damage repair. However, the detailed molecular mechanism remains elusive. Here, using unbiased protein affinity purification and RNA sequencing, it is found that TopBP1 is associated...
Autores principales: | Xin, Di, Gai, Xiaochen, Ma, Yidi, Li, Zexing, Li, Qilin, Yu, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558638/ https://www.ncbi.nlm.nih.gov/pubmed/37582658 http://dx.doi.org/10.1002/advs.202206931 |
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