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FGF9 Recruits β‐Catenin to Increase Hepatic ECM Synthesis and Promote NASH‐Driven HCC

Most nonalcoholic steatohepatitis (NASH) patients develop severe fibrosis through extracellular matrix (ECM) accumulation, which can lead to hepatocellular carcinoma (HCC). Fibroblast growth factor 9 (FGF9) is involved in serial types of cancer; however, the specific role of FGF9 in NASH‐driven HCC...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zhang, Qing, Teng, Da, Guo, Manyu, Tang, Kechao, Wang, Zhenglin, Wei, Xiang, Lin, Li, Zhang, Xiaomin, Wang, Xiuyun, Huang, Dake, Ren, Cuiping, Yang, Qingsong, Zhang, Wenjun, Gao, Yong, Chen, Wei, Chang, Yongsheng, Zhang, Huabing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558677/
https://www.ncbi.nlm.nih.gov/pubmed/37566761
http://dx.doi.org/10.1002/advs.202301166