Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins

Domain insertion engineering is a promising approach to recombine the functions of evolutionarily unrelated proteins. Insertion of light‐switchable receptor domains into a selected effector protein, for instance, can yield allosteric effectors with light‐dependent activity. However, the parameters t...

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Detalles Bibliográficos
Autores principales: Mathony, Jan, Aschenbrenner, Sabine, Becker, Philipp, Niopek, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558690/
https://www.ncbi.nlm.nih.gov/pubmed/37562980
http://dx.doi.org/10.1002/advs.202303496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558690/
https://www.ncbi.nlm.nih.gov/pubmed/37562980
http://dx.doi.org/10.1002/advs.202303496

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