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Adipose METTL14‐Elicited N(6)‐Methyladenosine Promotes Obesity, Insulin Resistance, and NAFLD Through Suppressing β Adrenergic Signaling and Lipolysis

White adipose tissue (WAT) lipolysis releases free fatty acids as a key energy substance to support metabolism in fasting, cold exposure, and exercise. Atgl, in concert with Cgi‐58, catalyzes the first lipolytic reaction. The sympathetic nervous system (SNS) stimulates lipolysis via neurotransmitter...

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Detalles Bibliográficos
Autores principales: Kang, Qianqian, Zhu, Xiaorong, Ren, Decheng, Ky, Alexander, MacDougald, Ormond A., O'Rourke, Robert W., Rui, Liangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558699/
https://www.ncbi.nlm.nih.gov/pubmed/37526326
http://dx.doi.org/10.1002/advs.202301645