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TRAF3IP2 drives mesenchymal stem cell senescence via regulation of NAMPT-mediated NAD biosynthesis

The cellular senescence of mesenchymal stem cells (MSCs) limits their application in regenerative medicine. This study aimed to clarify the role of TNF receptor-associated factor 3 interacting protein 2 (TRAF3IP2), a pro-inflammatory cytoplasmic adaptor protein, in regulating MSC senescence and to e...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoran, Liu, Baojuan, Liang, Yaowen, Mai, Cong, Shen, Ying, Huang, Xinran, Chen, Jiaqi, Liang, Xiaoting, Hu, Bei, Li, Weifeng, Li, Xin, Zhang, Yuelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558736/
https://www.ncbi.nlm.nih.gov/pubmed/37809895
http://dx.doi.org/10.1016/j.heliyon.2023.e19505