Drosophila Mpv17 forms an ion channel and regulates energy metabolism

Mutations in MPV17 are a major contributor to mitochondrial DNA (mtDNA) depletion syndromes, a group of inherited genetic conditions due to mtDNA instability. To investigate the role of MPV17 in mtDNA maintenance, we generated and characterized a Drosophila melanogaster Mpv17 (dMpv17) KO model showi...

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Detalles Bibliográficos
Autores principales: Corrà, Samantha, Checchetto, Vanessa, Brischigliaro, Michele, Rampazzo, Chiara, Bottani, Emanuela, Gagliani, Cristina, Cortese, Katia, De Pittà, Cristiano, Roverso, Marco, De Stefani, Diego, Bogialli, Sara, Zeviani, Massimo, Viscomi, Carlo, Szabò, Ildiko, Costa, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558772/
https://www.ncbi.nlm.nih.gov/pubmed/37810222
http://dx.doi.org/10.1016/j.isci.2023.107955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558772/
https://www.ncbi.nlm.nih.gov/pubmed/37810222
http://dx.doi.org/10.1016/j.isci.2023.107955

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