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Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren’s syndrome

Primary Sjögren’s syndrome (pSS) is a complex autoimmune disease characterized by lymphocytic infiltration and exocrine dysfunction, particularly affecting the salivary gland (SG). We employed single-cell RNA sequencing to investigate cellular heterogeneity in 11 patients with pSS and 5 non-SS contr...

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Detalles Bibliográficos
Autores principales: Xiang, Nan, Xu, Hao, Zhou, Zhou, Wang, Junyu, Cai, Pengfei, Wang, Li, Tan, Zhen, Zhou, Yingbo, Zhang, Tianping, Zhou, Jiayuan, Liu, Ke, Luo, Songwen, Fang, Minghao, Wang, Guosheng, Chen, Zhuo, Guo, Chuang, Li, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558796/
https://www.ncbi.nlm.nih.gov/pubmed/37810210
http://dx.doi.org/10.1016/j.isci.2023.107943