Identification of region-specific splicing QTLs in human hippocampal tissue and its distinctive role in brain disorders

Alternative splicing (AS) regulation has an essential role in complex diseases. However, the AS profiles in the hippocampal (HIPPO) region of human brain are underexplored. Here, we investigated cis-acting sQTLs of HIPPO region in 264 samples and identified thousands of significant sQTLs. By enrichm...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyan, Zhao, Yiran, Kong, Hui, Song, Chengcheng, Liu, Jie, Xia, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558811/
https://www.ncbi.nlm.nih.gov/pubmed/37810239
http://dx.doi.org/10.1016/j.isci.2023.107958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558811/
https://www.ncbi.nlm.nih.gov/pubmed/37810239
http://dx.doi.org/10.1016/j.isci.2023.107958

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