CDK4/6i enhances the antitumor effect of PD1 antibody by promoting TLS formation in ovarian cancer

Ovarian cancer is insensitive to immunotherapy and has a high mortality rate. CDK4/6 inhibitors (CDK4/6i) regulate the tumor microenvironment and play an antitumor role. Our previous research demonstrated that lymphocyte aggregation (tertiary lymphoid structures, TLSs) was observed after CDK4/6i tre...

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Detalles Bibliográficos
Autores principales: Feng, Wangyou, Jiang, Dongbo, Xu, Ying, Li, Yuanfeng, Chen, Lin, Zhao, Minye, Shen, Yujie, Liao, Wenjing, Yang, Hong, Li, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559077/
https://www.ncbi.nlm.nih.gov/pubmed/37809574
http://dx.doi.org/10.1016/j.heliyon.2023.e19760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559077/
https://www.ncbi.nlm.nih.gov/pubmed/37809574
http://dx.doi.org/10.1016/j.heliyon.2023.e19760

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