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CDK4/6i enhances the antitumor effect of PD1 antibody by promoting TLS formation in ovarian cancer
Ovarian cancer is insensitive to immunotherapy and has a high mortality rate. CDK4/6 inhibitors (CDK4/6i) regulate the tumor microenvironment and play an antitumor role. Our previous research demonstrated that lymphocyte aggregation (tertiary lymphoid structures, TLSs) was observed after CDK4/6i tre...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559077/ https://www.ncbi.nlm.nih.gov/pubmed/37809574 http://dx.doi.org/10.1016/j.heliyon.2023.e19760 |