Development of a CD8(+) T cell-based molecular classification for predicting prognosis and heterogeneity in triple-negative breast cancer by integrated analysis of single-cell and bulk RNA-sequencing

BACKGROUND: Triple-negative breast cancer (TNBC), although the most intractable subtype, is characterized by abundant immunogenicity, which enhances responsiveness to immunotherapeutic measures. METHODS: First, we identified CD8(+) T cell core genes (TRCG) based on single-cell sequence and tradition...

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Detalles Bibliográficos
Autores principales: Dai, Yin-wei, Wang, Wei-ming, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559128/
https://www.ncbi.nlm.nih.gov/pubmed/37810147
http://dx.doi.org/10.1016/j.heliyon.2023.e19798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559128/
https://www.ncbi.nlm.nih.gov/pubmed/37810147
http://dx.doi.org/10.1016/j.heliyon.2023.e19798

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