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Identification of FAM53C as a cytosolic-anchoring inhibitory binding protein of the kinase DYRK1A

The protein kinase DYRK1A encoded in human chromosome 21 is the major contributor to the multiple symptoms observed in Down syndrome patients. In addition, DYRK1A malfunction is associated with various other neurodevelopmental disorders such as autism spectrum disorder. Here, we identified FAM53C wi...

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Detalles Bibliográficos
Autores principales: Miyata, Yoshihiko, Nishida, Eisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559228/
https://www.ncbi.nlm.nih.gov/pubmed/37802655
http://dx.doi.org/10.26508/lsa.202302129