Ultrasound-targeted semaglutide-loaded PEG-nanoliposomes microbubble destruction protects diabetic cardiomyopathy by activating PI3K/Akt/Nrf2 signaling pathway

OBJECTIVE: To investigate the ameliorative effect of Semaglutide-loaded PEG-nanoliposomes (Sem-PEG-lips) combined with ultrasound-targeted microbubble destruction (UTMD) on streptozotocin (STZ)-induced diabetic cardiomyopathy (DCM) in rodents and its potential mechanisms. METHODS: Sem-PEG-lips were...

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Detalles Bibliográficos
Autores principales: Zhu, Jiawei, Wang, Huiyang, Yan, Chunyang, Li, Bin, Chen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559235/
https://www.ncbi.nlm.nih.gov/pubmed/37809373
http://dx.doi.org/10.1016/j.heliyon.2023.e19873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559235/
https://www.ncbi.nlm.nih.gov/pubmed/37809373
http://dx.doi.org/10.1016/j.heliyon.2023.e19873

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