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Ultrasound-targeted semaglutide-loaded PEG-nanoliposomes microbubble destruction protects diabetic cardiomyopathy by activating PI3K/Akt/Nrf2 signaling pathway
OBJECTIVE: To investigate the ameliorative effect of Semaglutide-loaded PEG-nanoliposomes (Sem-PEG-lips) combined with ultrasound-targeted microbubble destruction (UTMD) on streptozotocin (STZ)-induced diabetic cardiomyopathy (DCM) in rodents and its potential mechanisms. METHODS: Sem-PEG-lips were...
Autores principales: | Zhu, Jiawei, Wang, Huiyang, Yan, Chunyang, Li, Bin, Chen, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559235/ https://www.ncbi.nlm.nih.gov/pubmed/37809373 http://dx.doi.org/10.1016/j.heliyon.2023.e19873 |
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