Tobramycin-loaded nanoparticles of thiolated chitosan for ocular drug delivery: Preparation, mucoadhesion and pharmacokinetic evaluation

The present work aimed to develop nanoparticles of tobramycin (TRM) using thiolated chitosan (TCS) in order to improve the mucoadhesion, antibacterial effect and pharmacokinetics. The nanoparticles were evaluated for their compatibility, thermal stability, particle size, zeta potential, mucoadhesion...

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Detalles Bibliográficos
Autores principales: Javed, Sadaf, Abbas, Ghulam, Shah, Shahid, Rasul, Akhtar, Irfan, Muhammad, Saleem, Ammara, Hosny, Khaled M., Bukhary, Sahar M., Safhi, Awaji Y., Sabei, Fahad Y., Majrashi, Mohammed A., Alkhalidi, Hala M., Alissa, Mohammed, Khan, Sajid Mehmood, Hanif, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559273/
https://www.ncbi.nlm.nih.gov/pubmed/37809498
http://dx.doi.org/10.1016/j.heliyon.2023.e19877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559273/
https://www.ncbi.nlm.nih.gov/pubmed/37809498
http://dx.doi.org/10.1016/j.heliyon.2023.e19877

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