The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity

Kinesin-5 crosslinks and slides apart microtubules to assemble, elongate, and maintain the mitotic spindle. Kinesin-5 is a tetramer, where two N-terminal motor domains are positioned at each end of the motor, and the coiled-coil stalk domains are organized into a tetrameric bundle through the bipola...

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Detalles Bibliográficos
Autores principales: Nithianantham, Stanley, Iwanski, Malina K., Gaska, Ignas, Pandey, Himanshu, Bodrug, Tatyana, Inagaki, Sayaka, Major, Jennifer, Brouhard, Gary J., Gheber, Larissa, Rosenfeld, Steven S., Forth, Scott, Hendricks, Adam G., Al-Bassam, Jawdat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559304/
https://www.ncbi.nlm.nih.gov/pubmed/37610838
http://dx.doi.org/10.1091/mbc.E23-07-0287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559304/
https://www.ncbi.nlm.nih.gov/pubmed/37610838
http://dx.doi.org/10.1091/mbc.E23-07-0287

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