A dedicated cytoplasmic container collects extrachromosomal DNA away from the mammalian nucleus

Expression from transfected plasmid DNA is generally transient, but it is unclear what process terminates it. We show that DNA entering mammalian cells is rapidly surrounded by a double membrane in the cytoplasm, in some cases after leaving the nucleus. This cytoplasmic container, termed exclusome,...

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Detalles Bibliográficos
Autores principales: Schenkel, Laura, Wang, Xuan, Le, Nhung, Burger, Michael, Kroschewski, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559310/
https://www.ncbi.nlm.nih.gov/pubmed/37556227
http://dx.doi.org/10.1091/mbc.E23-04-0118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559310/
https://www.ncbi.nlm.nih.gov/pubmed/37556227
http://dx.doi.org/10.1091/mbc.E23-04-0118

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