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A dedicated cytoplasmic container collects extrachromosomal DNA away from the mammalian nucleus
Expression from transfected plasmid DNA is generally transient, but it is unclear what process terminates it. We show that DNA entering mammalian cells is rapidly surrounded by a double membrane in the cytoplasm, in some cases after leaving the nucleus. This cytoplasmic container, termed exclusome,...
Autores principales: | Schenkel, Laura, Wang, Xuan, Le, Nhung, Burger, Michael, Kroschewski, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559310/ https://www.ncbi.nlm.nih.gov/pubmed/37556227 http://dx.doi.org/10.1091/mbc.E23-04-0118 |
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